Plainpicture It may sound crazy, but many drugs, treatments and medical guidelines become common practice long before we know whether they work. Too often, we find out they don’t – and that they may even be harmful. (See The scary reality of medical U-turns) So how can you make sure your treatment has been put to the test? Adam Cifu, professor of medicine at the University of Chicago and co-author of the book Ending Medical Reversal, says it starts with asking your doctor the right questions. What questions do patients usually ask their doctors?